Aggressive Recurrent Basal Cell Carcinoma: A Case Report

Basal cell carcinoma (BCC) was first described in 1824 by Jacob who called it “ulcus rodens”: Its current nomenclature wasproposed by Krompecher in 1903. It is the most common type of nonmelanoma skin cancer and the most common malignancyin humans. BCC is typically slow-growing tumor, for which metastases are rare, it can be locally destructive and disfiguring. Thecurrent mainstay of BCC treatment involves surgical modalities such as excision, electrodessication and currettage, cryosurgery,and Mohs’ micrographic surgery. The rates of recurrence are variable in the literature, between 10% and 40 %.

Successful anesthetic management of a 17-year-old patient with facial arterio-venous undergoing sclerotherapy: a case report

Arterio-venous malformations (AVM) are abnormal collection of blood vessels. They are rare congential vascular malformations that account for 1.5% of all vascular abnormalities while 50% of such cases occur in the oral and maxillofacial region. Facial AVM are uncommon. Patients presenting with AVMs require a complete investigation using precise clinical examination and advanced imaging modalities. The treatment of a patient with AVM includes a multi-step process. In this case, we report a case of extensive AVM in the face of a 17-year-olf female patient. The report primarily focuses on the successful anesthetic management for sclerotherapy along with insights on clinical characteristics and imaging manifestations. To the best of our knowledge, this is one of the few cases to be reported in India.

Oral malignancy and its fickle blow off: A retrospective study

Background: The aim of this study was to retrospectively evaluate various patterns of failure in patients with oral squamous cell carcinoma and to estimate overall survival (OS) and disease-free survival (DFS) in failure patterns. Materials and Methods: Retrospective data of 500 patients operated for oral malignancy were obtained from year 2011 to 2014. Incidence of local, regional, and distant failure as well as DFS and OS was calculated. Furthermore, we studied various prognostic factors such as habits and coexistent comorbid conditions, depth of invasion, histological grade of tumor, and primary site of tumor. Results: Average DFS was 13.9 months and average overall survival was 55.77 months. The overall incidence of recurrence was 42.4%. Incidence of local recurrence was 24%, regional recurrence was 11.2%, and distant failure was seen in 7.2% of cases. Conclusion: Despite execution of standard treatment protocol comprising of surgery and chemoradiation, incidence of recurrence remains sententious in oral malignancy

Extra medullary multiple myeloma of knees: a case report

Multiple myeloma is defined as an incurable, complex, and rare malignant disease of the plasma cells. Multiple myeloma is characterized by uninhibited proliferation of clonal plasma cells. Extramedullary disease is characterized by the presence of clonal plasma cell infiltrate adjacent to soft tissues or distant from the bone marrow in patients with underlying MM. Survival of patients with MM is low. A 65-year-old female reports to the outpatient clinics with pain in the left lower limb for over 2 months. The patient had loss of range of motion. True-cut biopsy revealed multiple myeloma of synovial sarcoma. Extramedullary disease is considered as an uncommon manifestation of multiple myeloma. It is either a newly diagnosed disease or evolves with repeated relapses. There is no clear data on the incidence of extramedullary disease. Since there is a no standard treatment for extramedullary disease, its prognosis remains poor.

Rhabdomyosarcoma of Orbit: A Rare Case Report and Review.

Rhabdomyosarcoma (RMS) is a highly fulminant, mesenchymal malignant tumor and is considered to be one among life-threatening disease in the present decades. It is considered to be most common malignant neoplasm of the head and neck region with 10% of cases occurring in orbit. Th ough it is common in sixth and seventh decades, it can also occur in early childhood. In this article, we present a rare case of 9-yearold boy who was diagnosed with histopathologically proven RMS of orbit who had undergone a salvage left orbital exenteration following a chemotherapy. Th e main aim of this article is also to provide an overview of RMS of orbit, clinical features, investigations required, staging and various treatment modalities.